Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

But he told Washington's Observer-Reporter paper that he was keen to read it as it was "a testament of the sincerity, interest and innocence of that time".
此时可能会有旅客好奇,是否会有一座机场超过备受称赞的樟宜机场呢?
凭借这场胜利,金州勇士队追平了由1957-1958赛季的波士顿凯尔特人队创造的卫冕冠军赛季开局14连胜纪录。而勇士队也是成为在NBA历史上,仅有的五只以14胜0负开局的球队。接下来,他们将会作客丹佛,力争在周日将纪录继续保持下去。
China is committed to denuclearization of the Korean Peninsula, the peace and stability in the Korean Peninsula, and resolving issues through dialogue and consultation. That is China’s consistent and clear-cut position.
凭借这场胜利,金州勇士队追平了由1957-1958赛季的波士顿凯尔特人队创造的卫冕冠军赛季开局14连胜纪录。而勇士队也是成为在NBA历史上,仅有的五只以14胜0负开局的球队。接下来,他们将会作客丹佛,力争在周日将纪录继续保持下去。
The awards, announced during a ceremony in Amsterdam on March 14, are based on millions of international passenger surveys.
3.7 加大生态环境保护治理力度
我们认为中国2014年的经济成长会高速增加,增速会超过2013。而在美国的“中国问题专家”们,在面对中国稳定的超过7%的年增长率铁据之后,还会坚持唱衰中国的经济。
也许同等重要的是,稳定或者下降的油价将会缓解通货膨胀压力使美国工人的工资更具有购买力。Renaissance Macro经济学家Neil Dutta 称“这对于国内需求来说是一个明确的积极的消息,人们将会有更多可以用来消费的钱”。
8) I am a closed kind of person 0 1 2 3 4
积极扩大有效投资。
这部由塞巴斯蒂安.马拉比(Sebastian Mallaby)所著的《知者:格林斯潘传》(The Man Who Knew),是这项奖金额为3万英镑的奖项的第12位获奖者。该奖项奖励的是年度“最令人瞩目和愉悦的”图书。
注册营养师艾利克斯?图鲁夫称:“糖屑中含有糖分,而金片与此不同,它不含碳水化合物、脂肪或蛋白质,所以不能提供热量,没有味道,主要用于装饰。”
The Olympic games are a time when the countries of the world should put aside their differences to engage in sport. Whether that actually happens, however, is debatable. While the athletes are surely capable of focusing on the competition, it can be hard for long-standing disagreements to be forgotten -- even temporarily -- by their home countries.
The future is always bright if you are an entrepreneur, and the opportunities to create new ventures based on the digitisation of age-old services has a long way to run.
The Fifa World Cup is close by. Let me give you a few rules that will preserve your beauty.
['pre]
[tr?ns'p?:t]
“This is our make or break moment for the tenant movement,” said Ilana Maier, the program director for the Metropolitan Council on Housing. “If we aren’t able to drastically strengthen the rules now, none of this will matter in 10 years.”
9.The Company Isn't Doing Well
In a close second was Changsha, capital of Hunan province, with growth of 4.5.
If successful, the funding would underline the rapid growth of the sector this year. In April, Lufax raised $500m at a $10bn valuation.
《总督之房》
这个排行榜是不断变化的全球商业环境的年度快照。美国仍然是拥有最多数量的全球2000强公司的国家:总共564家。尽管今年日本失去的成员最多(26家),仍然尾随美国,总计拥有225家公司。
我国近日发行的2016年猴票同样由黄永玉创作。面值为每张1.2元钱,也颇受关注。在正式发布之前,收集者已经在邮局外排起了长队。


['minits]
6年来第一次,新的挑战者领衔英国《金融时报》高管MBA(EMBA)课程排行榜。
在排名靠前的学校中,英国华威商学院(Warwick Business School)排名提升最大,从第16位提升至第9名。整体而言,上海交通大学(Shanghai JiaoTong University)的上海高级金融学院(Shanghai Advanced Institute of Finance)排名提升最大,从第28位提升至第14位。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

单词securities 联想记忆:
中国政府确定的消费者物价通胀目标为3.5%,但增长日益疲弱将令物价指数变得温和。
"According to our survey last year, only 0.6 to 0.7 percent of students at universities were thinking about starting their own companies. The number among vocational school students was as high as 2.2 percent. However, the idea of vocational students starting businesses is related more to creating jobs for themselves, and the majority of them have chosen to have online shops."
周二,她在给客户的一封信里提出了下面几个观点,令我耳目一新:

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

这款智能产品的使用可以追溯到1800年,但在2016年它才变得“智能”。 Meet Peggy,这种洗衣挂钩能够“帮助你减轻负担”,它会在洗衣机洗好衣服的时候提醒你,并告诉你天气是否适宜晾晒衣服。该装置连接到您的手机,它会在天气变化或是需要转移晾衣服的地方时发消息提醒你。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

An escalating war on drugs in the Philippines has led to almost 1,800 deaths under new president Rodrigo Duterte, the country’s police chief has said.
据《每日经济新闻》报道,这16家上市银行计划向股东返还3562亿元现金分红,与前一年相比减少了83亿元。

发行于2013年的《炫富帮》是一部语带讽刺的犯罪剧情片,记录了一帮好莱坞山高中生的冒险,他们偷到了当地名人的家里。少年们进入梅根·福克斯和帕丽斯·希尔顿这样的偶像家,偷走现金、衣服、手袋和珠宝,用来模仿杂志上让他们羡慕的奢华生活。在朋友圈炫耀战利品的照片后,他们终于被抓进了监狱。
Bank of China posted earnings per share of Rmb0.56, down from Rmb0.61, and a pre-tax dividend per share of Rmb0.175, down from Rmb0.19 last year.
The controlled test takes two-and-a-half hours and, according to theories, Nishi's score and subsequentIQ of 162 would be two points higher than famous physicist Einstein.
这位工作人员说道:“她注册时说自己姓韩,也不是像媒体上报道的姓苏。”
供给侧结构性改革:去产能、去库存、去杠杆、降成本、补短板
Changing minds

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


温州房产垫资5天利率4-6分 民资投实业比重仅24%


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


在这月初这封信上写着的地址是宾夕法尼亚大学的某个邮箱。
QK%.jd&KnAkQ
促进外贸继续回稳向好。
n. 感动(激动,愤怒或震动), 搅拌,骚乱
A Method to the Madness
East New York in Brooklyn will be the test case when the Department of City Planning presents initial recommendations early next year. After that, the rezoning process could begin for the neighborhood, among the city’s poorest. A proposal for west Flushing in Queens is next.
4. 外包就业服务
11月24日至25日,苏富比举办慕尼黑第四代交易商康拉德·伯恩海默(Konrad Bernheimer)的藏品拍卖会,他拥有历史悠久的伦敦科尔纳吉画廊(Colnaghi)。65岁的伯恩海默决定缩小自己的业务,关闭慕尼黑的画廊,卖掉巴伐利亚的豪华宅邸马尔库斯泰恩城堡(Marquartstein Castle),将科尔纳吉画廊与伦敦的Coll & Cortes画廊合并。
China’s bid to close its own Asia-Pac deal
农业原材料,特别是所谓的软性大宗商品,例如糖、咖啡和棉花,今年的表现在最佳之列。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the 教育企业高管的薪酬均值倒数第一,刚过280万元,约为金融业高管薪酬的1/10。 to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

一次投入全部很少能够成功。虽然确实有人倾其所有,在六个月或一两年之后成为赢家,但这只是个案。对于任何初创公司来说,风险管理都是一个重要元素,账目平衡至关重要。如果你在最开始承担的风险更少,你就更容易消化损失。而这些损失将是必不可少的、富有价值的教训。
创业者之间竞争的本质在于效率。好消息是,如今市面上已经有了好几千种优秀的应用软件,能令我们的生活变得更加轻松,但是你不可能有足够的时间把这几千种应用都试上一遍。那么,哪些应用值得你花时间试用一下呢?
One suggested change: require rent-stabilized tenants to verify their income.
The University of St Gallen’s domination of the Financial Times’ ranking of masters in management courses continues for another year.

《国土安全》(Homeland):第三季末布洛迪(Brody,戴米恩·路易斯[Damian Lewis]饰)最终被杀后,映时频道(Showtime)的这部间谍惊悚剧似乎走到了尽头。目前看来,第四季没了他却变得充满活力,令人喜爱。卡莉(Carrie,克莱尔·丹尼斯[Claire Danes]饰)这次的对手是美貌、狡猾的巴基斯坦情报官塔斯尼姆(Tasneem,尼姆拉特·考尔[Nimrat Kaur]饰)。

  • Only the first three authors are listed, followed by "et al."
  • 国务院扩大升级信息消费 智能家居迎机遇
  • 2017年中国建筑陶瓷制品行业市场竞争格局分析


爆发冲突的潜在可能性,将迫使中国和美国在不断变幻的环境中重新定义各自的角色,双方都对这种环境感到不安。美国大选期间的反华情绪将使紧张气氛加剧。亚洲国家将勾勒出这两个大国的影响力范围,但考虑到各国的利益各有不同,取决于各自的具体关切,联盟的构成也将变化。
“I was quite sceptical initially in doing an online course but the communication and online interaction were perfect,” says one graduate from AGSM.

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