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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

[?'pru:v?l]
判断权在你手里。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 居然在线上线 全面迎战“双11”
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Learn to control your emotions, control your thoughts, get over fear of rejection and learn to open up.
D1t]!J^-6h=kwFS)I

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 家居行业 “阵痛”中求变寻新机
Open Access Perspective

Soft matter science and the COVID-19 pandemic

The Good Place

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

12. Is there something I am clinging to? We don’t always realize when we’re clinging to something harmful when it feels safe and familiar, whether it is an unfulfilling job, an unhealthy relationship, or a stagnant way of life. Recognize if you are clinging to something that isn’t serving you and work on taking small steps towards change and release.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

He also posted a picture of himself looking at a racially diverse group of children.
8月24日
现在,Swyft一半的收入都来自于为格温o史蒂芬尼制作的这类广告。雷表示,Swyft每月收入的增长幅度在50% 到100%之间。另一半就来自销售贴纸——主要是靠知名运动队和《怪物史莱克》这样的娱乐品牌授权。
adj. 无限的,无穷的

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

In this April 24, 1984, file photo, from left, Steve Jobs, chairman of Apple Computers, John Sculley, president and CEO, and Steve Wozniak, co-founder of Apple, unveil the new Apple IIc computer in San Francisco
7.Yes, John was with me last night. – Because that’s what friends do… we agree and ask questions later。
The QUBE will remind you to recycle, monitor when the trash was last taken out, and tell you to change the air freshener. These are all things people usually remember to do anyway, by the smell and all, but now there's a $300 "elegant" stainless steel can that'll constantly remind you with annoying mobile alerts.
作为门户网站,雅虎将移动技术作为扭转厄运的重中之重。它将目光投向了英国少年尼克达洛伊西奥(Nick D'Aloisio)和Summly,后者能够为小屏幕设备自动生成新闻摘要。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

单词affection 联想记忆:

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

['pl?nit]

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Federica Mogherini, the EU’s foreign policy chief, and Johannes Hahn, the bloc’s enlargement commissioner, have also weighed in, criticising Mr Erdogan’s proposed constitutional changes and his recent rhetoric.
IMD participants praised the way their training pushed them out of their comfort zones and also the one-on-one coaching sessions tailored to their individual business situations. “It was an eye opener about what a good leader is,” commented one participant. “We learnt about ourselves first, what drives us and why, in order to manage others.”

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

指数:93.6
德系三巨头:由于奔驰的几款低价产品不可避免地会损害它“要么最好,要么什么都不是”(the best or nothing)的商誉,该公司也开始陷入低迷。而即将推出的新7系轿车则会进一步巩固宝马在美国富人圈中的地位。另外,起价30,795美元的奥迪A3,很可能会使奥迪的销量较2014年增长15%,新款Q7也将进一步提高奥迪的利润。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.
2016年,中国电影票房经历了一次令人震惊的调整,从2015年的48%大幅下降到3.7%。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

About 980 million yuan of illicit assets were recovered, according to the Communist Party of China Central Commission for Discipline Inspection.
[.dem?'kr?tik]
星巴克首席执行官霍华德舒尔茨
Warm hearted wishes for a happy New Year filled with all your favorite things.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

米尔德里德的女儿7个月前遇害,但凶手仍然逍遥法外,主角一怒之下做出了一个大胆的决定:买下了小镇入口三张广告牌并在张贴图片中抨击颇有威望的警长威廉?威洛比。威廉的副手官迪克逊是一个幼稚的妈宝男,有暴力倾向。迪克逊卷入这件事后,米尔德里德和小镇执法系统之间的较量变得愈发激烈了。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

一位新浪微博网友写道:“不敢相信这么多医生都在论文中造假。病人还能相信他们可以帮人治病吗?”
As a result, his position on the Forbes' ranking dropped 220 spots, leaving him tied with 19 others as the 544th richest person in the world.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Snap, however, has sunk to about $15 after initially rallying from its IPO price of $17 in March, damping some expectation of further activity involving so-called decacorns, tech companies that have achieved valuations of $10bn or more through private funding.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Yu Xiuhua, born with cerebral palsy, lived a quiet village life. She is now a literary sensation whose vivid, erotic poems are “stained with blood.”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

He did several makeup tests to get the look that would so dramatically change Mr. Carell. “We were literally creating a new human being,” Mr. Corso said.
But only 14,000 tourists took advantage of the visa-free stopover, according to the Beijing General Station of Exit and Entry Frontier Inspection, well short of the 20,000 target officials had previously predicted.
They need more talent. Full stop. The best avenue for attracting talent for them has always been the draft.
分析师们认为,这次新机发布将有助于苹果克服过去两年的增长问题。在像美国和欧洲这样的市场上,智能手机的拥有量已趋近饱和,很多客户不再频繁更换现有手机,推动更快收入增长的最佳途径就是提高单位价格,而不是单纯地依靠出货量。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

坚持依法全面履职。
尽管金融行业整体趋势向上,但相较于男性,女老板执掌的企业筹得的资金历来处于落后状态。例如,2013年上半年,寻求融资的企业中,老板是女性的企业仅占16%,而其中又仅有24%的女性接受了天使资金。Plum Alley是一家为女性创业者提供在线商务服务的平台,最近该公司推出了一个专注于帮助女性创新者推进到下一个事业阶段的众筹平台。作为呈现爆炸式增长趋势的众筹领域(预计明年规模将达到39.8亿美元)中的首个此类平台,我们应该能看到Plum Alley在未来一年中在女性创业领域扮演重要角色。
2. Smart water bottle
potential
It might be that bit too far from the mainstream to make a huge awards impact.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

卢华东表示:“今年是西藏反贫困的重要时期,我们将根据不同情况和引起贫困的原因,继续制定政策和计划,并持续增加资金。”
The pandas did some tai-chi in Trafalgar Square before kicking on at a panda party in Convent Garden as part of the first ever Panda Awareness Week.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Elspeth Cheung, head of BrandZ valuation at Millward Brown, says: “The top 10 used to be dominated by consumer goods. This year, it’s technology.”

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

“Airbnb将生存下去,”戈特塞根表示,“与其抗拒它,我们不如拥抱它、改善它。”

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

会是除巴西、德国和西班牙之外的国家捧得大力神杯吗?
每个伟大的侦探都需要专属于自己的经典故事。对于福尔摩斯而言,这个故事是《巴斯克维尔的猎犬》。对于阿加莎?克里斯蒂笔下龟毛的比利时侦探赫克尔?波洛而言,这个故事是《东方快车谋杀案》——故事讲述了一个嗜血的恶棍在驶向巴尔干半岛的列车上杀死了一个有钱的商人。真相果真是如此吗?西德尼?吕美特曾在1974年将该故事拍成了一部备受喜爱的电影,强大的演员阵容包括肖恩?康纳利、英格丽?褒曼和阿尔伯特?芬尼(饰演侦探波洛)。如今肯尼思?布拉纳自己戴上了侦探波洛的大胡子,披挂上阵,同时又担当幕后导演。这部新版电影的演员有约翰尼?德普、黛西?雷德利、米歇尔?菲佛、佩内洛佩?克鲁斯和朱迪?丹奇。这个故事还能挖掘出什么新内容呢?也许会有。不过,即使没有,阿婆的粉丝也肯定会去看。这部电影将于11月3日在英国上映,11月10日在美国、中国和土耳其上映,11月30日在中国香港和新加坡上映。(资料来源:二十世纪福克斯电影公司)
每个人都喜欢饼干,但是买一个智能烤箱似乎可以多烤一点。这个烤箱承诺在短短10分钟内就烤好饼干,但不考虑时间的因素,使用老式的烤箱似乎更容易做更多饼干。
新兴市场出口额(以美元计算)下滑完全是一种价格效应,受到大宗商品价格下降的拖累。从数量上看,新兴市场出口自2014年以来一直持续上升,即便同比年增长率已放缓至2%左右——远远低于全球金融危机前后的两位数增长率,如第二张图表所示。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

在纽约举办了多次其标志性的时装秀之后,内衣品牌维多利亚的秘密又来到伦敦、巴黎、戛纳和洛杉矶举办维密秀,而在2017年,该全球女士内衣行业巨头来到了上海。
Whiteness means being part of the group whose appearance, traditions, religion and even food are the default norm. It’s being a person who, by unspoken rules, was long entitled as part of “us” instead of “them.”
达洛伊西奥说,我本来只是打算在苹果app store用一两英镑的价格出售这个软件,然后用赚来的钱给自己换台新电脑。我之前从没联系过任何投资商。而如今一个香港的亿万富翁竟然给我发电邮了,这太诡异了。第一封邮件我没有回覆,于是他们又给我发了第二封。2011年8月份,他的父母带着不可置信的心情陪他一同与维港投资的代表进行了会面。会谈结束后,达洛伊西奥获得了30万美元的种子投资。
Letizia Battaglia chronicled Palermo’s Mafia wars in the 1970s and ’80s for a local newspaper. Now, her images appear in museums and retrospectives.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

n. 经营方法,行为态度
fT0awloSPOsF,bqnZ)

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Snapchat on Tuesday launched Discover, a section of its app where media outlets including Vice, CNN andPeople magazine can publish video content within Snapchat. Already several of the channels feature ads, which aren’t cheap. According to Adweek, Snapchat ads cost $750,000 per day.
The number of students who will study abroad after graduation has also seen a drop, down from 4.8 percent last year to 3.4 percent.
At tech start-up conferences, such as Slush in Helsinki in December, everyone was talking about experiences. The coming year is likely to see a wider adoption of virtual reality, which places the user in a digitally enhanced environment, and augmented reality, which overlays digital information on to the real world, creating new digital businesses.
去年12月份达成的预算协议很难称得上是华盛顿激辩多年所希望看到的、能够提振信心的协议,但至少它为华盛顿不断上演的政治博弈按下了“暂停”键。在过去三年中,华盛顿每年都会上演的这种博弈对经济的复苏构成了威胁。
At school, even in kindergarten, you teach us to behave in the world. You teach us: not to fight with others, to respect others, to clean up our mess, not to hurt other creatures, to share - not be greedy. 在学校,甚至在幼稚园,你们大人教我们如何处世,你们告诉我们不要打架,要尊重对方。找出答案,解决矛盾。去分享,而不是贪婪。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

纽约人向专栏提出的问题,不仅取决于他们的个人情况,还取决于当今的重大问题,比如住房成本上升、士绅化、豆腐渣工程。最终,2014年成为了一个一切都在增长的年份,增长的包括房价、租金,以及最重要的——楼盘数量。根据纽约房地产委员会(Real Estate Board of New York)的数据,10月批准建设的单元达到了16700套。
然而一般情况下,你只需注意洗衣机是否停止发出噪声就能来判断洗衣服是否结束。另外你也只要抬头一看外面的天气或者看一下天气预报app,就能知道是否会下雨了。因此,这个产品基本上只是一种黑客进入你家的方式。
当我表示自己对一门很难的课程十分害怕时,我的指导老师问我:“那你还想不想接受教育呢?”

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The .40-calibre Smith & Wesson that killed her, a semi-automatic handgun, was seized by police to undergo ballistics testing to determine if it had been used in other crimes.
1. glitterati / n . 知名人 士,国际上层社会人士。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 10月建材家居销量普涨但低于预期
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

最后,不管你是什么性格的人,积极生活,健康向上!
Some of the leaked photos and videos can still be found on Chinese social media as of press time.
“Even though I’m an engineer and an analytical person at heart, the most important decisions I’ve ever made had nothing to do with any of that,” he told an interviewer at Duke University, where he studied for an MBA, last year. “They were always based on intuition.”

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

8.A New iPhone
桑迪已经造成大规模损害,很可能带来更多灾害。
由人社部社会保险事业管理中心近日发布的这项报告显示,企业职工养老保险基金的收益率达到3.1%,创6年来新高。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

[in'spekn]

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 中小型卫浴企业如何制定营销战略
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

还有些人直接就玩消失了:

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 房企资金趋紧暂难改
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

新上榜学校中排名最高的是巴黎第九大学(Université Paris-Dauphine),排在第57位。
给我一点空间

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

不论是在那首一目了然的《IDGAF》(《我才不在乎呢》)中对情人的不屑一顾,还是在那首狂热的《Lost in Your Light》(《迷失在你的光芒中》)与米格尔热烈的音乐相和,她以些许艾蕾莎·贝丝·摩儿那种深沉的态度和些许希雅那种令人受不了的夸张,强烈地表达着自己的情感,但她也是一位比这两人都要热情的歌手。
The worst of 2015
Temperatures in 2015 also shattered the previous record set in 2014 by 0.13C, according to Nasa.
It is just a common sense that no one wants to see chaos at his doorstep.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 资本退潮 长租公寓重新洗牌
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

It's time to make New Year resolutions for traveling! Backpacker bible Lonely Planet has published its annual list of best value destinations in 2017 for people looking for wallet-friendly sightseeing experiences. Take a look.
时间:2011-11-03 编辑:Lily

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

达福目前可能是最佳男配角的领跑者。
对于更多的普通投资者而言,在标普500指数回报高于历史平均值的大背景下,2014年是充满挫折的一年。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

You're the best present I ever received.你是我所收到的最好的礼物。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

尽管此次维密秀备受期待,但似乎该内衣品牌在中国的首秀并没有完全按计划进行。
The same seven schools continue to dominate the top half of the ranking. AGSM at UNSW Business School of Australia entered the ranking for the first time in eighth position.
8. Smile every time EXCEPT when my team is losing.
Fluctuations of the markets led to a tightening of IPO approval to maintain stability, according to Frank Lyn, PwC China's mainland and Hong Kong Markets Leaders.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

(实际上,在过去三年的节日假期里,捷蓝航空公司绝对不是航班起飞延误最糟糕的航空公司。这项殊荣要授予Comair公司,这是达美航空公司经营地区航线的公司。不过该公司在2012年假日季节开始前停业,因此我们没有让这家公司上榜。)
Yes, it is that obvious when you're interviewing elsewhere and go MIA, with or without a flimsy excuse. Schedule phone interviews for personal hours, like a lunch break, and take vacation or PTO days for lengthy in-person interviews. "That way, you're not feeling pressured during the interview to get back to work – which can affect how you handle the interview – and you're not stealing time from your employers," Kay says。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

9. 安布罗斯·阿钦摩西尔(Ambrose Akinmusire),《想像中的救世主更容易描绘》(the imagined savior is far easier to paint),Blue Note。小号手安布罗斯·阿钦摩西尔为自己在Blue Note公司发行的第二张专辑注入了类型不固定,富于探索精神的今日之声,有许多歌手和一支弦乐四重奏组合参与。和这张专辑刚发行的时候相比,如今的他有了更多评论社会的迫切与讥讽时局的精神。
过去一年中,亚利桑那州最大的赢家是建筑和休闲/酒店行业,这两个行业共增加了超过1万个就业机会。其他快速增长的行业包括商业服务、金融活动、教育和医疗服务。
单词productive 联想记忆:

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

智能手机巨头小米创始人雷军同意此观点,将AlphaGo的取胜描述为人工智能领域的突破。
这份报告还指出,中国现在共有594名以美元计的亿万富翁,这一数字超越了美国的535名,但是并没有一名中国富翁进入全球首富前20名。
creative

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

9月12日,苹果将在位于库比蒂诺(Cupertino)的新总部举行产品发布会,届时备受期待的10周年纪念版iPhone预计将会亮相,这款智能手机的显示屏、摄像头和总体设计都会有重大升级。
卢彦说,通州和其他地区也会建设高规格的医院供市中心地区居民看病,该举措可以缓解交通压力和城市拥堵。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 2016年LED显示屏企业并购渐趋理性
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The .40-calibre Smith & Wesson that killed her, a semi-automatic handgun, was seized by police to undergo ballistics testing to determine if it had been used in other crimes.
在主持过去年的奥斯卡颁奖典礼、之前的格莱美奖及艾美奖之后,她无疑是这个角色的最佳选择。
Yes — just. Democrats will regain control of the House of Representatives in the November midterm elections. Though they will not take charge until January 2019, they will waste no time preparing the House Judiciary paperwork. Mr Trump will label it a “witch hunt”. But another year of his surreal presidency makes it all but inevitable Democrats will campaign on a pledge to hold him to account. Whatever Robert Mueller’s investigation unearths before then is unlikely to turn enough Republicans against him.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

威廉凯特夫妇多次让加拿大人等候多时,例如,抵达加拿大时,两人花了20分钟时间才从飞机上下来接受加方欢迎团队的问候。
Recipient: Lindsay Lohan

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

谁来主持2014年奥斯卡颁奖典礼?
When I am creating a light novel, Iam creating it mostly alone. When I am working on anime there is a director andthe staff with a point of view on my works. There usually are several revisionsregarding the storyboard. What is interesting is what will come back. It's avery interesting part of the work.
Attention, travel lovers. You may not have made any travel plans yet, but the choices for next year’s best destinations are already out. Recently, the well-known travel guide publisher Lonely Planet issued its Best in Travel 2014 selection. Here, we pick a few countries from its top 10 list to give you a taste.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

在最新发布的年度最受欢迎旅游目的地榜单上,泰国首都曼谷重回首位。此前数年曼谷一直徘徊在榜单第二名。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

“同为南方的儿子和疯狂的体育迷,我向你脱帽致敬,”前美国总统比尔?克林顿(Bill Clinton)发了一条推特(tweet)回应库克的文章。
devastating

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

['p?st]
500个品牌来自28个不同国家,其中近半(227个)来自美国。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

他有能力向球迷们展示接下来的计划吗?——不管是什么计划。在又一个无论场内场外都丑陋的赛季后,尼克斯球迷当然有理由知道上述两个问题的答案。
新年英文祝福语大全

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

周二在上海举办的中国国际机器人产业发展高峰论坛称,2017年,工业机器人的销量和增速均创新高。在这些工业机器人当中,有37825台为国产制造,同比增长29.8%。
在你死后,数以百计的基因会突然活跃起来,而且还会继续活动长达4天。3月份的一个实例表明,在人死后,尸体的大脑还会活动长达10分钟,连同这个无法解释的实例,我们开始意识到我们所了解的死亡依然保有一些奇怪的生命迹象。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

在韩国首都首尔,20%年龄介于19到49岁的女性承认她们为了改变样貌,接受过美容整形手术。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

根据美国海洋和大气管理局的数据,美国本土今年1月至11月的气温是有史以来每年前11个月的最高记录。2012年还将超过1998年,成为美国有记录以来最热的一年。
福布斯表示,如果不扣除管理费和税费,在2015年6月1日到2016年6月1日期间,全球收入最高的10位女星共入账2.05亿美元。
In 2013, the yuan appreciated almost 3% against the U.S. dollar, making 'Beijing a more expensive destination than in the past,' Jiang Yiyi noted.
decline

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

这是一次及时的预警。他写道,自己的研究结果“表明,随着美联储继续实施利率正常化,未来几年新兴市场爆发危机的风险将加剧。”

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

巴西
“狗屎。都在说谎,都是权宜之计,他们不过是想让自己好受些,我知道这些人都是胆小鬼,只要表面上看起来能凑合,对他们来说这就够了。”
Stand: Yahoo CEO Marissa Mayer defended work-from-home ban

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

China has become the world's largest industrial robot market since 2013, and currently its domestic suppliers are moving up the supplier chain by offering more high-end products in recent years, added the report.
自2007年4月以来,全球最具价值品牌100强的品牌价值增长106%。同期标准普尔500指数(S&P 500)和MSCI明晟全球指数(MSCI world index)分别上涨61%和21%。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

chann管道+el表名词,“人或物”→航道
项目管理类

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Paul George, Chris Paul, Carmelo Anthony, Gordon Hayward Jimmy Butler, Derrick Rose, Paul Millsap, J.J. Redick, Eric Bledsoe, Dwight Howard ... the list goes on and on of players who switched uniforms since last year.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 京津冀限行 水性涂料要火
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The drama got 7.2 points on Douban, receiving criticism for having too much romance and too few of Zhou's struggles.
The data was released to encourage the adoption of stronger passwords. Mr Slain added:"As always, we hope that with more publicity about how risky it is to use weak passwords, more people will start taking simple steps to protect themselves by using stronger passwords and using different passwords for different websites."
在苹果今年6月举行的全球开发者大会(Worldwide Developer Conference)上,库克被应用开发者团团围住,要求与他自拍合影。到了10月的iPad发布会,他甚至自己讲起了笑话。他还是一贯的着装,简单朴实:黑衬衫,牛仔裤,衬衫下摆散着。他说,Apple Watch得到了“深谙时尚与风格——比我还懂的人”的热烈好评,一边说,一边心照不宣地指着轻声发笑的观众。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Total Program Cost: $98,906
自从1995年游戏第一次面世以来,续集和新版本在之后也接踵而来。但是,对于许多仙剑迷来说,《仙剑1》激动人心又充满悲伤的故事情节是其他任何版本也代替不了的。
vi. 流通,循环,传播
But then the story took a strange turn. Koudijs and Voth found that Dutch lenders reacted to the Seppenwolde collapse in strikingly different ways. Those who had made loans to Seppenwolde but hadn’t actually lost money became far more pessimistic and demanded much bigger haircuts from all new borrowers. But those who had dodged the bullet by not lending to Seppenwolde didn’t tighten their requirements at all. In fact, those lenders slightly reduced haircuts to their borrowers – a sign they were at least as sanguine as before.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 中介欠房租 承租人被判搬离
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Prices at China's factory gates fell for a 34th consecutive month in December, pushed down by falling energy and commodity prices.
v. 从事运

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

随着二孩生育政策的出台,为了缓解女性的担忧,国家应明确规定禁止歧视女性,包括要求公司有一定比例的女员工以及减税或其他优惠措施,以鼓励雇主有效实施女职工产假延长的规定。
vi. 打结
尽管给股东的分红正在缩水,但这些银行的分红数额仍占据中国所有上市企业分红总额的一半。去年,这16家银行报告的盈利占据上市公司盈利总额的52%。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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In a humiliating 111-77 loss to the Golden State Warriors at Oracle Arena, Bryant shot 1-of-14 from the field, including 1-of-7 from 3-point range, and scored four points. He also shot 1-of-14 in a loss last season to the San Antonio Spurs.
I wish you a happy New Year. All affection and best wish

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